Figure 1.

5.8 Gy and 6.5 Gy irradiation exposure results in significantly increased exosomal shedding. Using quantitative ELISA targeting CD63, a well-known marker for exosomes, plasma-derived exosome samples were quantified. After exposure to ⁶⁰Co γ-radiation, an increase in the number of isolated exosomes was noted. Exosome counts at 7-d prior, 1 d post- and 14 d post-irradiation with (A) 5.8 Gy or (B) 6.5 Gy ⁶⁰Co γ-radiation. p-values: ns = not significant, * = <0.05, ** = <0.01.