Figure 2.

Comparison of the model simulated growth dynamics with experimental data. Solutions to the proposed model (Equations (3)–(10)) were obtained after performing data fitting (estimated parameters are presented in Table 1). (A) Experimental and simulated tumor volumes for tumors grown without treatment or after monotherapy. (B) Experimental and simulated tumor volumes after combination treatment. Experimental data (red circles) derived from Dewan et al. [11].