Table 1.
Identification of P450s that are involved in secondary metabolite BGCs in Bacillus species. BGCs in each species and P450 identified as part of a particular cluster are presented in Supplementary Dataset 5.
| Species Name | Cluster Number | Type of BGCs | P450 Name |
|---|---|---|---|
| Bacillus subtilis subsp. subtilis 168 | 4 | Nrps-Transatpks-Otherks | CYP134A1 |
| 10 | Other | CYP134A1 | |
| Bacillus subtilis subsp. subtilis RO-NN-1 | 3 | Nrps-Transatpks-Otherks | CYP107K1 |
| Bacillus subtilis subsp. subtilis BSP1 | 8 | Transatpks-Otherks-Nrps | CYP107K1 |
| Bacillus subtilis subsp. subtilis 6051-HGW | 4 | Nrps-Transatpks-Otherks | CYP107K1 |
| 10 | Other | CYP107K1 | |
| Bacillus subtilis subsp. subtilis BAB-1 | 4 | Nrps-Transatpks-Otherks | CYP107K1 |
| Bacillus subtilis subsp. subtilis AG1839 | 4 | Nrps-Transatpks-Otherks | CYP107K1 |
| 10 | Other | CYP107K1 | |
| Bacillus subtilis subsp. subtilis JH642 | 4 | Nrps-Transatpks-Otherks | CYP107K1 |
| 10 | Other | CYP134A1 | |
| Bacillus subtilis subsp. subtilis OH 131.1 | 1 | Lantipeptide | CYP152A1 |
| 4 | Nrps-Transatpks-Otherks | CYP107K1 | |
| 9 | Other | CYP134A1 | |
| Bacillus subtilis subsp. spizizenii W23 | 1 | Phosphonate | CYP152A1 |
| 4 | Nrps-Transatpks-Otherks | CYP107K1 | |
| 10 | Other | CYP134A1 | |
| Bacillus subtilis subsp. spizizenii TU-B-10 | 3 | Nrps-Transatpks-Otherks | CYP107K1 |
| 9 | Other | CYP134A1 | |
| Bacillus subtilis BSn5 | 4 | Other | CYP102A48 |
| 8 | Lantipeptide | CYP152A1 | |
| 11 | Nrps-Transatpks-Otherks | CYP107K1 | |
| Bacillus subtilis QB928 | 4 | Nrps-Transatpks-Otherks | CYP107K1 |
| 10 | Other | CYP134A1 | |
| Bacillus subtilis XF-1 | 4 | Nrps-Transatpks-Otherks | CYP107K1 |
| Bacillus subtilis PY79 | 4 | Nrps-Transatpks-Otherks | CYP107K1 |
| 9 | Other | CYP134A1 | |
| Bacillus licheniformis ATCC 14580 | 7 | Other | CYP134A5 |
| Bacillus licheniformis DSM 13 = ATCC 14580 | 7 | Other | CYP134A5 |
| Bacillus paralicheniformis | 10 | Other | CYP134A5 |
| Bacillus velezensis FZB42 | 5 | Transatpks-Nrps | CYP107K3 |
| 6 | Transatpks-Nrps | CYP107H4 | |
| 9 | Transatpks | CYP113L1 | |
| Bacillus velezensis CAU B946 | 5 | Transatpks-Nrps | CYP107K3 |
| 6 | Transatpks-Nrps | CYP107H4 | |
| 9 | Transatpks | CYP113L1 | |
| Bacillus velezensis YAU B9601-Y2 | 5 | Transatpks | CYP107K3 |
| 6 | Transatpks-Nrps | CYP107K3 | |
| 7 | Transatpks-Nrps | CYP107H4 | |
| 10 | Transatpks | CYP113L1 | |
| Bacillus velezensis AS43.3 | 6 | Transatpks | CYP107K3 |
| 7 | Transatpks-Nrps | CYP113L1 | |
| 10 | Transatpks | CYP113L1 | |
| Bacillus velezensis UCMB5036 | 5 | Transatpks-Nrps | CYP107K3 |
| 6 | Transatpks-Nrps | CYP107H4 | |
| 9 | Bacteriocin-Nrps | CYP113L1 | |
| Bacillus velezensis UCMB5033 | 6 | Transatpks-Nrps | CYP107K3 |
| 7 | Transatpks-Nrps | CYP107H4 | |
| 10 | Transatpks | CYP113L1 | |
| Bacillus velezensis UCMB5113 | 7 | Transatpks-Nrps | CYP107K3 |
| 8 | Transatpks-Nrps | CYP107H4 | |
| 11 | Transatpks | CYP113L1 | |
| Bacillus velezensis NAU-B3 | 3 | Transatpks | CYP113L1 |
| 6 | Transatpks-Nrps | CYP107H4 | |
| 7 | Transatpks-Nrps | CYP107K3 | |
| Bacillus velezensis TrigoCor1448 | 5 | Transatpks-Nrps | CYP107K3 |
| 6 | Transatpks-Nrps | CYP107H4 | |
| Bacillus velezensis SQR9 | 6 | Transatpks-Nrps | CYP107K3 |
| 7 | Transatpks-Nrps | CYP107H4 | |
| 10 | Transatpks | CYP113L1 | |
| Bacillus velezensis | 6 | Transatpks-Nrps | CYP107K3 |
| 7 | Transatpks-Nrps | CYP107H4 | |
| 10 | Transatpks | CYP113L1 | |
| Bacillus amyloliquefaciens DSM 7 | 5 | Transatpks-Nrps | CYP107K3 |
| 6 | Transatpks-Nrps | CYP107H2 | |
| Bacillus amyloliquefaciens TA208 | 7 | Transatpks-Nrps | CYP107H2 |
| 8 | Transatpks-Nrps | CYP107K3 | |
| Bacillus amyloliquefaciens LL3 | 5 | Transatpks-Nrps | CYP107K3 |
| 6 | Transatpks-Nrps | CYP107H2 | |
| Bacillus amyloliquefaciens XH7 | 7 | Transatpks-Nrps | CYP107H2 |
| 8 | Transatpks-Nrps | CYP107K3 | |
| Bacillus amyloliquefaciens Y2 | 6 | Transatpks-Nrps | CYP107K3 |
| 7 | Transatpks-Nrps | CYP107H4 | |
| 10 | Transatpks | CYP113L1 | |
| Bacillus amyloliquefaciens IT-45 | 3 | Transatpks | CYP113L1 |
| 6 | Transatpks-Nrps | CYP107H4 | |
| 7 | Transatpks-Nrps | CYP107K3 | |
| Bacillus amyloliquefaciens CC178 | 6 | Transatpks-Nrps | CYP107H4 |
| 9 | Transatpks | CYP113L1 | |
| Bacillus amyloliquefaciens LFB112 | 7 | Transatpks-Nrps | CYP107K3 |
| 8 | Transatpks-Nrps | CYP107H4 | |
| 11 | Transatpks | CYP113L1 | |
| Bacillus atrophaeus 1942 | 3 | Nrps-Transatpks-Otherks | CYP107K2 |
| 10 | Nrps | CYP152A9 | |
| Bacillus atrophaeus NRS 1221A | 3 | Nrps-Transatpks-Otherks | CYP107K2 |
| 10 | Nrps | CYP152A9 | |
| Bacillus vallismortis | 6 | Transatpks-Nrps | CYP107K3 |
| 7 | Transatpks-Nrps | CYP107H4 | |
| 10 | Transatpks | CYP113L1 | |
| Bacillus pumilus SH-B9 | 8 | Nrps | CYP109B6 |
| Bacillus sp. JS | 4 | Nrps-Transatpks-Otherks | CYP107K1 |
| Bacillus sp. Pc3 | 1 | Bacteriocin-Transatpks-Nrps | CYP107H4 |
| 2 | Transatpks-Nrps | CYP107K3 | |
| 10 | Transatpks | CYP113L1 | |
| Bacillus sp. BH072 | 8 | Transatpks-Nrps | CYP107K3 |
| 9 | Transatpks-Nrps | CYP107H4 | |
| 12 | Transatpks | CYP107H4 | |
| Bacillus sp. YP1 | 4 | Nrps-Transatpks-Otherks | CYP107K1 |
| Bacillus sp. BS34A | 4 | Nrps-Transatpks-Otherks | CYP107K1 |
| 10 | Other | CYP134A1 | |
| Bacillus sp. LM 4-2 | 3 | Nrps-Transatpks-Otherks | CYP107K1 |
| 7 | Other | CYP102A48 | |
| 9 | Other | CYP134A1 | |
| Bacillus gibsonii | 1 | Nrps-Transatpks-Otherks | CYP107K1 |
| 6 | Other | CYP134A1 | |
| 9 | Lantipeptide | CYP152A1 | |
| Bacillus xiamenensis | 2 | Nrps | CYP1179A4 |
| Bacillus altitudinis | 2 | Nrps | CYP1179A4 |
| 8 | Nrps | CYP109B5 | |
| Bacillus sp. SDLI1 | 3 | Transatpks-Nrps | CYP107H4 |
| 4 | Transatpks-Nrps | CYP107K3 | |
| 11 | Transatpks | CYP113L1 |