Histological evaluation of the mice retina at 16, 24, and 32 weeks (w) of age. Data are presented as mean ± SD. (a) Thickness of total retina, * p = 0.032 (t-test), ** p = 0.010 (T2D mice between 16 and 32 weeks of age, Kruskal-Wallis test followed by Dunn’s test); and (b) Thickness of photoreceptors, * p = 0.028 (t-test), ** p = 0.004 (T2D mice between 16 and 32 weeks of age, Kruskal-Wallis test followed by Dunn’s test) were measured in T2D and control mice retina; (c) Ganglion cell numbers were counted in T2D and control mice retina, * p = 0.003 (t-test), ** p = 0.023 (T2D mice between 16 and 32 weeks of age, Kruskal-Wallis test followed by Dunn’s test).