Table 3.
Imaging Study Findings in Children with ARP or CP by PD Status
| Pancreas Divisum=Yes (n=52) |
Pancreas Divisum=No (n=307) |
p-value | |
|---|---|---|---|
|
| |||
| Imaging studies performed | |||
| ERCP | 37 (71%) | 158 (51%) | <0.01 |
| Number ERCP (range) | (1–12) | (1–9) | |
| 1 | 21 | 88 | |
| 2 | 7 | 36 | |
| 3 | 5 | 14 | |
| ≥4 | 4 | 20 | |
| CT scan | 27 (52%) | 150 (49%) | 0.68 |
| MRI | 35 (67%) | 226 (74%) | 0.34 |
| EUS | 9 (17%) | 39 (13%) | 0.36 |
|
| |||
| Findings (any imaging) | |||
| Focal Acute Pancreatitis | 5/36 (14%) | 33/240 (14%) | 1.0 |
| Inflammatory changes | 14/36 (39%) | 84/242 (35%) | 0.62 |
| Enlarged Pancreas | 7/36 (19%) | 55/242 (23%) | 0.65 |
| Cysts/Pseudocysts | 10/52 (19%) | 49/307 (16%) | 0.55 |
| Peripancreatic inflammation/fat stranding | 16/39 (41%) | 82/246 (33%) | 0.34 |
| Gallstones/Sludge | 3/36 (8%) | 16/241 (7%) | 0.72 |
| Pancreatic Atrophy | 11/37 (30%) | 70/245 (29%) | 0.88 |
| PD stricture | 15/49 (31%) | 70/295 (24%) | 0.30 |
| PD irregularities | 20/36 (56%) | 97/245 (40%) | 0.07 |
| PD dilatation | 21/36 (58%) | 101/246 (41%) | 0.05 |
| Calcifications | 4/37 (11%) | 24/243 (10%) | 0.77 |
| CBD stricture | 2/51 (4%) | 18/305 (6%) | 0.75 |
| CBD dilatation | 8/52(15%) | 58/306 (19%) | 0.53 |
| CBD stones | 1/52 (2%) | 25/307 (8%) | 0.14 |
| Intraheptic biliary dilatation | 4/36 (11%) | 27/245 (11%) | 1.0 |
| Abnormal Side Branches | 18/50 (36%) | 80/296 (27%) | 0.19 |
| Changes suggestive of cirrhosis and/or portal hypertension | 2/36 (6%) | 13/241 (5%) | 1.0 |
| Main Pancreatic Duct - Abnormal | 33/52 (63%) | 160/303 (53%) | 0.15 |
| Intraductal filling defects of calculi | 9/52 (17%) | 57/300 (19%) | 0.77 |
ARP: Acute Recurrent Pancreatitis; CP: Chronic Pancreatitis; PD, pancreas divisum; ERCP, endoscopic retrograde cholangiopancreatography; CT, computed tomography; MRI, magnetic resonance imaging; EUS, endoscopic ultrasound; CBD, common bile duct
Significant p values are highlighted