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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: J Immunol. 2018 Oct 29;201(11):3320–3328. doi: 10.4049/jimmunol.1800670

Figure 6.

Figure 6.

Reduction of T cells was found in the periphery in 8-week-old Klotho-deficient mice that can be prevented by deprivation of vitamin D.

(A) Frequency and (B) cellularity of CD4T and CD8T cells in the spleen from Kl/Kl mice and littermate controls at 8 weeks of age. (C) Frequency and (D) cellularity of CD44hi memory-like T cells subpopulations in the spleen from Kl/Kl mice and littermate controls at 8 weeks of age. (E) Frequency and (F) cellularity of CD4T and CD8T cells in the spleen from 8-wk-old Kl/Kl mice and littermate controls fed with vitamin D-deprived diet. Each symbol in the graphs represents an individual mouse (n ≥ 4); small horizontal lines indicate the group mean (± s.d.). ns, not significant (P ≥ 0.05); *, P < 0.05.