Table 1.
Ferritin and mortality, by region and level of adjustment
| HR (95% CI) of ferritin (ng/mL) |
|||||||
|---|---|---|---|---|---|---|---|
| Region | 20 | 100 | 200 | 400 | 700 | 1000 | 1400 |
| USA (Ref = 718 ng/mL) | |||||||
| Model 1 | – | – | 0.92 (0.77–1.09) | 0.94 (0.85–1.04) | 1.00 (0.99–1.00) | 1.10 (1.05–1.14) | 1.29 (1.19–1.40) |
| Model 2 | – | – | 0.87 (0.73–1.04) | 0.92 (0.83–1.01) | 0.99 (0.99–1.00) | 1.09 (1.05–1.13) | 1.24 (1.14–1.35) |
| Model 3 | – | – | 0.83 (0.68–1.01) | 0.89 (0.80–1.00) | 0.99 (0.99–1.00) | 1.07 (1.03–1.12) | 1.16 (1.06–1.27) |
| Europe (Ref = 405 ng/mL) | |||||||
| Model 1 | – | 1.06 (0.90–1.25) | 1.03 (0.93–1.14) | 1.00 (1.00–1.00) | 1.09 (1.02–1.15) | 1.28 (1.18–1.40) | – |
| Model 2 | – | 1.03 (0.87–1.22) | 1.01 (0.91–1.13) | 1.00 (1.00–1.00) | 1.08 (1.02–1.15) | 1.25 (1.15–1.36) | – |
| Model 3 | – | 1.05 (0.89–1.25) | 1.03 (0.92–1.15) | 1.00 (1.00–1.00) | 1.06 (0.99–1.12) | 1.19 (1.08–1.30) | – |
| Model 4 | – | 1.09 (0.92–1.30) | 1.05 (0.94–1.18) | 1.00 (1.00–1.00) | 1.03 (0.97–1.09) | 1.14 (1.04–1.25) | – |
| Model 5 | – | 1.10 (0.93–1.31) | 1.06 (0.95–1.18) | 1.00 (1.00–1.00) | 1.02 (0.96–1.09) | 1.12 (1.02–1.23) | – |
| Japan (Ref = 83 ng/mL) | |||||||
| Model 1 | 1.00 (0.80–1.25) | 1.00 (0.96–1.05) | 1.06 (0.87–1.28) | 1.27 (1.01–1.60) | – | – | – |
| Model 2 | 0.97 (0.78–1.21) | 1.01 (0.96–1.06) | 1.07 (0.88–1.29) | 1.23 (0.98–1.53) | – | – | – |
| Model 3 | 1.04 (0.83–1.32) | 0.99 (0.95–1.04) | 1.00 (0.81–1.22) | 1.12 (0.89–1.40) | – | – | – |
| Model 4 | 1.07 (0.85–1.36) | 0.99 (0.94–1.04) | 0.97 (0.79–1.19) | 1.07 (0.85–1.34) | – | – | – |
| Model 5 | 1.06 (0.84–1.35) | 0.99 (0.94–1.04) | 0.98 (0.80–1.20) | 1.07 (0.85–1.34) | – | – | – |
HR and 95% CIs of Figure 3A–C models at specified ferritin levels.