Table 1.

HLA alleles and chemokine receptor genotypes relevant to the outcome of HIV-1 infection.

	Genes	Phenotypes	References
HLA	B*57a	Slow	(10–22, 54)
	B*27a	Slow	(21, 23–25, 54)
	B*6701, B*5201-C*1202	Slow	(26, 27)
	B*5801	Slow	(28)
	C1 C*1403 C*1202b	Slow Suppression of viral replication Lower pVL and higher CD4 counts	(30) (32) (31, 32)
	C: SNP(-35 C)a	Slow	(12, 13, 33–35, 38)
	C: SNP(-35 T)	Rapid	(13, 34, 36, 38)
	A*02b	Resistance, Lower risk in Mother-Child transmission	(41, 48)
	A*11 A*7401	Resistance Slow	(42) (43)
	B*18	Slow; Lower risk in Mother-Child Transmission	(44, 50)
	B*40b	Slow Susceptible	(44) (42)
	B*14 or B*1402	Slow	(24, 46)
	C8	Slow	(24)
	B*81	Slow	(45)
	B*5101	Slow	(47)
	A*02b-Cw*16	Increased VL	(51)
	A*02-B*45-Cw*16	Increased VL
	B*08	Rapid	(8)
	A*24	Rapid	(55)
	A*29	Increased risk in Mother-Child Transmission	(50)
	B*7	Rapid, B-clade infection	(56)
	B*35-Px: B*3502, B*3503, B*3504, B*5301 Putative B*35-Px: B*3509 Putative B*35-Py: B*3505b	Rapid Increased VL Increased VL in Peruvians	(54, 58) (59)
		Slow in Thais	(29)
	B*35-Py: B*3501b	Slow Increased VL	(61) (62)
	A, B −21M	Rapid	(9)
	DQB1*0603 DQB1*0609, DQB1*050301, DQA1*010201-DQB1*0603, DQB1*0302 DQB1*0602	Resistant Resistant Resistant Rapid; Susceptible	(65, 66) (65) (67) (65, 66)
	DQA1*010201-DQB1*0602,	Susceptible	(65)
	DQA1*0504-DQB1*0201,
	DQA1*010201-DQB1*0201,
	DQA1*0402-DQB1*0402,
	DQA1*0402-DQB1*030101
	DR2	Susceptible; Susceptible to HIV+PTB	(42) (68)
	HLA-B*35	Increased risk in superinfection	(69)
	HLA-C*04,	Increased risk in superinfection
	HLA-DRB1*08	Increased risk in superinfection
Chemokine	CCR5D32a	Resistant; Slow	(70–75)
Receptors	CCR5-59029A/G	Slow	(76, 77)
	CCR2V64I	Slow; Less susceptible	(78, 79)

^aProtective effect deduced from multiple independent studies.

^bControversial roles in disease progress.