Table 2. Patient characteristics during ICU stay.
Characteristics | Survivors (n=63) | Nonsurvivors (n=30) | P value |
---|---|---|---|
At VAP diagnosis | |||
Early-onset VAP | 19 [30] | 8 [27] | 0.729 |
Duration of mechanical ventilation before VAP occurrence | 9 [5, 15] | 9 [5, 18] | 0.522 |
Appropriate antibiotic treatment | 62 [98] | 26 [87] | 0.019* |
Duration of prior antimicrobial treatment, d | 7 [3, 13] | 8 [6, 11] | |
SOFA score | 5 [4, 9] | 8 [6, 13] | 0.005 |
Respiratory system | 2 [2, 3] | 3 [3, 4] | 0.045 |
Nervous system | 1 [1, 3] | 2 [1, 3] | 0.071 |
Cardiovascular system | 0 [0, 1] | 3 [0, 4] | 0.009 |
Liver | 0 [0, 0] | 0 [0, 2] | 0.085 |
Coagulation | 0 [0, 1] | 0 [0, 2] | 0.025 |
Kidneys | 0 [0, 1] | 0 [0, 2] | 0.038 |
CPIS | 9 [7, 10] | 9 [8, 11] | 0.117 |
Percentage of time spent with hyperoxemia, mean ± SD | 40±30 | 40±34 | 0.647 |
During ICU stay | |||
Total duration of antimicrobial treatment | 18 [11, 28] | 17 [14, 26] | 0.856 |
Duration of mechanical ventilation | 24 [13, 48] | 26 [16, 43] | 0.851 |
Length of ICU stay | 29 [20, 61] | 25 [15, 47] | 0.291 |
Percentage of time spent with hyperoxemia during the 7 days preceding VAP, mean ± SD | 48±28 | 45±23 | 0.731 |
Percentage of time spent with hyperoxemia during the 7 days subsequent to VAP, mean ± SD | 48±24 | 40±24 | 0.167 |
Data are presented as n [%] or median [interquartile range], unless otherwise indicated. *, OR (95% CI): 0.10 (0.01–0.98). VAP, ventilator-associated pneumonia; SOFA, sequential organ failure assessment; CPIS, clinical pulmonary infection score; ICU, intensive care unit.