Table 2.
Cycle characteristics and IVF/ICSI outcomes in controls compared to PCOS patients
| Variables | Control group | IR group | IS group | P value |
|---|---|---|---|---|
| n=8 | n=7 | n=8 | ||
| Number of follicles | 14.14 ± 1.55 | 18.25 ± 1.67 | 14.75 ± 2.30 | NS |
| Number of oocytes retrieved | 16.43 ± 1.45 | 13.00 ± 1.68 | 12.38 ± 1.92 | NS |
| Number of MII oocytes | 15.43 ± 1.23a | 10.88 ± 1.27b | 9.88 ± 1.22c | a, b=0.048 |
| a, c=0.015 | ||||
| Regular fertilization rate, % (# of 2PN/# MII oocytes) | 72 (78/108) | 69 (54/78) | 68 (54/79) | NS |
| Total embryos | 10.14 ± 0.86 | 7.25 ± 1.25 | 8.00 ± 1.18 | NS |
| Number of good quality embryos | 5.14 ± 0.83a | 200. ± 0.78b | 1.62 ± 0.60c | a, b=0.016 |
| a, c=0.005 | ||||
| Number of ET | 1.00 ± 0.49 | 1.75 ± 0.53 | 1.13 ± 0.44 | NS |
Variables are presented as Mean ± SE. P values determined with significance level of P<0.05. PCOS; Polycystic ovary syndrome, IVF; In vitro fertilization, ICSI; Intracytoplasmic sperm injection, IS; Insulin sensitive, IR; Insulin resistant, MII; Metaphase II oocytes, NS; Not significant, 2PN; Two pronuclei, ET; Embryos transferred, a, b ; Statistically significant differences between IR patients vs. controls, and a,c ; Statistically significant differences between IS patients vs. controls.