Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A high throughput FLIPR screen identifies a thiadiazole series of small molecule hTRPA1 inhibitors. (A) Examples of literature TRPA1 antagonists. (B) Compound 1 structure. (C) SAR of the thiadiazole series showing substitution patterns, mean FLIPR IC50 (n = 3–12 per compound), and cLogP.
