Table 1.

MdG hydrolysis in free DNA and NCPs

	kHyd,* ×10−7 s−1		t1/2,* h
MdG position	Free DNA	NCP	Free DNA	NCP	t1/2 (NCP:free DNA)
73	17.4 ± 1.1	13.9 ± 1.2	111 ± 7	139 ± 12	1.3
89	10.1 ± 0.5	3.5 ± 0.2	191 ± 8	550 ± 27	2.9
123	5.7 ± 0.1	1.0 ± 0.1	338 ± 6	1,930 ± 197	5.7
158	22.1 ± 2.0	9.9 ± 1.0	87 ± 8	194 ± 20	2.2

^*Values are the average ± SD of two experiments, each carried out in triplicate.