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. Author manuscript; available in PMC: 2018 Dec 3.
Published in final edited form as: Brain Behav Immun. 2017 May 27;65:111–124. doi: 10.1016/j.bbi.2017.05.018

Figure 3. PTPσ deletion facilitates infiltration of CD4+ T cells and activation of macrophages in spinal cord and brain.

Figure 3

(A–C) Markers for immune cells, including CD4, CD11b and CD45, were used to isolate subsets of T cells, macrophages and microglia by FACS from fresh brain and spinal cord 18 days after immunization. PTPσ−/− mice exhibit increased numbers of IFNγ+ and IL17+ CD4+ T cells, CD11b+CD45Hi macrophages and CD11b+CD45Int microglia monocytes. n = 3–5 mice/group.