Table 3. . Associations of pre- and early-pregnancy physical activity and candidate miRNAs.

miRNA	Prepregnancy								Early pregnancy
	Duration (hours per week)				Energy expenditure (MET hours per week)				Duration (hours per week)				Energy expenditure (MET hours per week)
	n	Est†	95% CI	p-value	n	Est†	95% CI	p-value	n	Est†	95% CI	p-value	n	Est†	95% CI	p-value
miR-146b-5p	75	0.084	0.017–0.151	0.02	75	0.017	0.001–0.033	0.03	74	0.017	-0.110–0.144	0.80	74	-0.041	-0.213–0.131	0.65
miR-126-3p	75	0.070	-0.01–0.150	0.09	75	0.012	-0.006–0.030	0.19	74	-0.015	-0.162–0.132	0.84	74	0.019	-0.181–0.219	0.85
miR-155-5p	75	0.050	-0.032–0.132	0.24	75	0.008	-0.012–0.028	0.39	74	0.027	-0.124–0.178	0.72	74	0.005	-0.199–0.209	0.96
miR-210-3p	74	0.066	-0.024–0.156	0.15	74	0.016	-0.004–0.036	0.12	73	0.018	-0.145–0.181	0.83	73	-0.043	-0.264–0.178	0.70
miR-21-3p	75	0.071	-0.021–0.163	0.14	75	0.013	-0.009–0.035	0.22	74	0.053	-0.116–0.222	0.54	74	0.098	-0.131–0.327	0.40
miR-222-3p	75	0.074	-0.002–0.150	0.07	75	0.017	-0.001–0.035	0.06	74	0.003	-0.140–0.146	0.97	74	-0.020	-0.214–0.174	0.84
miR-223-3p	75	0.079	-0.001–0.159	0.06	75	0.014	-0.004–0.032	0.14	74	-0.001	-0.148–0.146	0.99	74	0.037	-0.163–0.237	0.71
miR-29a-3p	75	0.055	-0.031–0.141	0.22	75	0.013	-0.007–0.033	0.20	74	0.023	-0.134–0.180	0.78	74	0.009	-0.205–0.223	0.93
miR-517-5p	73	0.060	-0.032–0.152	0.20	73	0.013	-0.009–0.035	0.22	72	0.021	-0.148–0.190	0.81	72	-0.156	-0.379–0.067	0.17
miR-518a-3p	74	0.073	-0.045–0.191	0.23	74	0.016	-0.011–0.043	0.25	73	0.052	-0.169–0.273	0.65	73	-0.004	-0.306–0.298	0.98

Results were similar after adjustment for prepregnancy BMI and smoking.

^†Model is adjusted for maternal age (years) and gestational age at blood draw (weeks). Outcome is log transformed.

MET: Metabolic equivalent.