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. 2018 Nov 21;3(11):15850–15864. doi: 10.1021/acsomega.8b02139

Figure 9.

Figure 9

Alleviation of 5-FU-induced mitochondrial oxidative damage by IADB + 5-FU treatment confirmed by direct visualization of the tissue oxidative status: mitochondrial oxidative status was evaluated in myocardial tissues using mtROS fluorescent probe (MitoProbe). Representative fluorescent stained images of myocardium derived from the 5-FU-treated rat cohort (A) and IADB + 5-FU rat cohort (red: MitoProbe fluorescence; blue: Hoechst 33342 fluorescence) (B). (C) Interactive 3D surface plots of merged images and (D) Interactive 3D surface plots of merged images (fire LUT images).