Figure 2.

NIR laser-controlled photothermal drug release from DOX@CAuNCs. (A) Temperature change of PBS, CCM, DOX, AuNCs, CAuNCs and DOX@CAuNCs upon 808 nm laser irradiation (1 W/cm²) for different time intervals. (B) Photothermal stability of AuNCs, CAuNCs and DOX@CAuNCs in PBS subjected to four cycles of 808 nm laser irradiation (1 W/cm²) and then cooling at room temperature. (C) In vitro DOX release kinetics from DOX@CAuNCs in PBS at pH 7.4 in the presence or absence of 808 nm laser irradiation (1 W/cm²) for 5 min. Black arrows indicate the irradiation points. Data as mean value ± SD (n=3).