Table 1.
Demographic and clinical characteristics
| Demographics | Control (N = 14) | SCA6 (N = 14) | PFDR value |
|---|---|---|---|
| Sex (female: male) | 10:4 | 10:4 | 1.00 |
| Handedness (left: right) | 1:13 | 4:10 | 0.56 |
| Hand tested (left: right) | 4:10 | 5:9 | 0.82 |
| Age (years) | 63.6 (6.8) | 65.8 (7.9) | 0.82 |
| MVC (N) | 64.1 (18.8) | 50.1 (24.1) | 0.23 |
| MoCA: total | 27.4 (1.5) | 24.5 (2.9) | 0.02 |
| ICARS: kinetic | - | 10.4 (6.2) | - |
| ICARS: total | - | 27.3 (14.8) | - |
| SARA: total | - | 11.0 (6.2) | - |
Data are sums or means (±SD)
Note that handedness was self-reported; more affected hand, which was self-reported, was used for SCA6 and either dominant or non-dominant hand assigned randomly was used for controls
ICARS International Cooperative Ataxia Rating Scale, MoCA montreal cognitive assessment, MVC maximum voluntary contraction, PFDR corrected P value using a false discovery rate, SARA scale for the assessment and rating of ataxia, SCA6 spinocerebellar ataxia type 6