Table 3.
Difference of task-based functional connectivity between control and SCA6 groups
| Brain region (s) | Side | Size (mm3) | MNI coordinates (Peak) |
t value | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| M1 (−24, −21, 74) | C | |||||
| CON > SCA6 | ||||||
| Vs. vermis VI, Lobule I–IV, V, VI | 3294 | 3 | −66 | −15 | 6.40 | |
| Vs. SMA | C | 378 | −9 | −3 | 54 | 4.14 |
| Vvs. SMA, preSMA | I | 378 | 6 | 9 | 51 | 3.83 |
| SCA6 > CON | ||||||
| Vs. M1, PMd | C | 675 | −45 | −9 | 57 | 3.41 |
| M1 (27, −15, 72) | I | |||||
| CON > SCA6 | ||||||
| Vs. vermis VI | 648 | 3 | −66 | −12 | 3.30 | |
| SMA, preSMA (−2, −6, 72) | C | |||||
| CON > SCA6 | ||||||
| Vs. vermis VI, Lobule I–IV, V, VI | I | 4995 | 24 | −66 | −18 | 4.21 |
| Vs. lobule VI | I | 486 | 36 | −48 | −30 | 3.94 |
| Vs. crus I | C | 324 | −42 | −72 | −24 | 4.73 |
| SMA (3, −3, 57) | I | |||||
| CON > SCA6 | ||||||
| Vs. lobule V | I | 2376 | 9 | −57 | −15 | 5.62 |
C contralateral hemisphere, CON control, I ipsilateral hemisphere, M1 primary motor cortex, MNI Montreal Neurological Institute, PMd dorsal premotor, SMA supplementary motor area, SCA6 spinocerebellar ataxia type 6