Table 1.
Differentially expressed genes (FDR < 0.10)
| FC Threshold | Comparison | No. increased | No. decreased | Total |
|---|---|---|---|---|
| None | 6 hours | 678 | 480 | 1158 |
| 24 hours | 726 | 297 | 1023 | |
| 48 hours | 446 | 107 | 553 | |
| 6–48 hours | 1320 | 799 | 2119 | |
| Pooleda | 1724 | 1155 | 2867 | |
| FC > 1.50 or FC < 0.67 | 6 hours | 228 | 115 | 343 |
| 24 hours | 246 | 36 | 282 | |
| 48 hours | 285 | 29 | 314 | |
| 6–48 hours | 265 | 30 | 295 | |
| Pooleda | 634 | 182 | 812 |
aPooled: Number of genes significantly altered by GM6 (FDR < 0.10) at the indicated FC threshold in any of the 4 comparisons performed (i.e., 6, 24, 48, or 6–48 h)
The table lists the number of differentially expressed genes (DEGs) significantly altered by GM6 in SH-5YSY neuroblastoma cells. All genes were significantly altered at an FDR threshold of 0.10 and we tabulated the number of unique DEGs with and without an additional FC threshold (first column). Differential expression analyses were performed with respect to each time point (6, 24 and 48 h). We additionally identified genes with evidence for a consistent differential expression pattern with respect to each of the 3 time points (6–48 h) as well as genes differentially expressed in any of the 4 comparisons (pooled)