Table 1.
Description of data, according to study group.
| Total | Case | Control | |||
|---|---|---|---|---|---|
| N = 266 | N = 32 | N = 234 | |||
| Variable | n (%)a | n (%)a | Odds ratio (95% CI) | P value | |
| Sex | 0.243 | ||||
| Female | 149 | 21 (65.6) | 128 (54.7) | 1 | |
| Male | 117 | 11 (34.4) | 106 (45.3) | 0.63 (0.29, 1.38) | |
| Age in years, mean (SD) | 58.8 (16.9) | 38.8 (22.3) | 61.6 (14.0) | <0.001 | |
| <60 years | 120 | 26 (81.3) | 94 (40.2) | 6.45 (2.47, 16.90) | |
| 60+ years | 146 | 6 (18.8) | 140 (59.8) | 1 | |
| Biopsy siteb,c | |||||
| Ileum | 115 | 16 (50.0) | 99 (42.3) | 1.36 (0.65, 2.86) | 0.410 |
| Colon | 225 | 19 (59.4) | 206 (88.0) | 0.20 (0.09, 0.46) | <0.001 |
| Cecum | 8 | 1 (3.1) | 7 (3.0) | 1.05 (0.12, 8.83) | 0.828 |
| Appendix | 11 | 10 (31.3) | 1 (0.4) | 105.9 (9.25, >1000) | <0.001 |
| Rectum | 40 | 15 (46.9) | 25 (10.7) | 7.38 (3.12, 17.4) | <0.001 |
| Histological diagnosis | <0.001 | ||||
| Infection/inflammation | 64 | 24 (75.0) | 40 (17.1) | 7.08 (2.49, 20.11) | |
| Infection+polyps/hyperplasia | 13 | 2 (6.3) | 11 (4.7) | 2.15 (0.37, 12.49) | |
| Polyps/hyperplasia | 35 | 0 (0.0) | 35 (15.0) | na | |
| Neoplasia | 85 | 0 (0.0) | 85 (36.3) | na | |
| Ischemia/fibrosis | 5 | 1 (3.1) | 4 (1.7) | 2.95 (0.27, 31.70) | |
| No abnormality | 64 | 5 (15.6) | 59 (25.2) | 1 | |
| Clinical signs | <0.001 | ||||
| Yes | 138 | 32 (100) | 106 (45.3) | na | |
| No | 128 | 0 (0.0) | 128 (54.7) | 1 | |
| Chlamydiaceae detected | <0.001 | ||||
| Yes | 4 | 4 (12.5) | 0 (0.0) | na | |
| No | 262 | 28 (87.5) | 234 (100) | 1 |
aNumbers presented are mean and standard deviation for age.
bTotal is greater than 276 because patients could have biopsy from more than one site.
cOdds ratio calculated separately for each site comparing cases and controls.
Abbreviations: na, not available (odds ratio could not be calculated because of zero count in one cell); SD, standard deviation.