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Dextran-Catechin induced downregulation of GSH in SK-N-BE(2)-C tumor cells. L-BSO was used a positive control of GSH reduction (A). Representative western blot (B) and densitometry analysis (C) showing that the expression of Copper transporter 1 (CTR1) is not reduced by Dextran-Catechin (DC 20µg/mL) in the presence of the proteasome inhibitor MG132 (10µM). Data obtained as mean of at least three experiments, deviation calculated as SEM (**: p < 0.01; ***: p < 0.001; ****: p < 0.0001).
