Figure 2.

Changes in the percentages of classical and intermediate monocytes after injection of ASCs. (A) Representative image of a dot plot to identify the three monocytes subsets with the corresponding percentage. Quantification of CD14⁺ classical monocytes (B), CD14⁺CD16⁺ intermediate monocytes (C), and CD14^dimCD16⁺ patrolling monocytes (D) at day 0 (D0, circles), day 7 (D7, squares), 1 month (M1, triangles) and 3 months (M3, inverted triangles) after injection of different amounts of ASCs (red = 2x10⁶ cells, green= 10x10⁶ cells, blue 50x10⁶ cells) in individual patients with severe OA; *p<0.05.