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. 2018 Nov 10;8(20):5662–5675. doi: 10.7150/thno.28241

Figure 4.

Figure 4

Evaluation of the therapy effect in vitro. Western blot analysis of intracellular survivin protein after Lip 2000 and QD@M-DNA/FA transfected antisense oligonucleotide (A); flow cytometry of the apoptosis induced by Lip 2000 and QD@M-DNA/FA transfection of antisense oligonucleotide (B) (n=3) ; MTT assay of survival rate of HeLa cells treated with different probes (C); fluorescence imaging of calcein staining HeLa and A549 cells irradiated by laser (2 W/cm2) for 10 min after incubation with QD@M-db, QD@M-db/FA and QD@M/D-DNA/FA for 2 h (D), the white dashed line was the irradiation boundary. **: p<0.01.