TABLE 3.
Depression, Counseling/Support Group Attendance, and Social Support as Predictors of Progression to WHO Stage III/IV HIV Disease in Univariate and Multivariate Analyses, n = 893*
| Univariate Relative Hazard (95% CI) |
P | Multivariate Relative Hazard I (95% CI) |
P | Multivariate Relative Hazard II (95% CI) |
P | |
|---|---|---|---|---|---|---|
| Depression | 1.57 (1.26 to 1.97) | <0.0001 | 1.55 (1.23 to 1.95) | 0.0002 | 1.61 (1.28 to 2.03) | <0.0001 |
| Individual counseling/peer group | ||||||
| Never | — | — | 1.00 | 1.00 | ||
| At least once | 0.96 (0.79 to 1.17) | 0.700 | 1.02 (0.84 to 1.25) | 0.825 | ||
| Baseline social support | ||||||
| Low (<10th percentile) | — | — | 1.22 (0.82 to 1.81) | 0.332 | 1.11 (0.74 to 1.66) | 0.604 |
| Not low | 1.00 | 1.00 | ||||
| CD4+ lymphocyte count (µL) at enrollment | ||||||
| <200 | — | — | — | — | 2.47 (1.77 to 3.46) | <0.0001 |
| 200–499 | 1.42 (1.14 to 1.79) | 0.002 | ||||
| 500+ | 1.00 | |||||
| Educations (y) | ||||||
| None/less than 5 | — | — | — | — | 1.68 (1.10 to 2.58) | 0.017 |
| 5–8 | 1.43 (1.02 to 2.01) | 0.039 | ||||
| 9+ | 1.00 | |||||
| Occupation | ||||||
| None outside the home | 1.00 | |||||
| Office | 1.63 (1.02 to 2.58) | 0.039 | ||||
| Business | — | — | — | — | 1.06 (0.81 to 1.38) | 0.692 |
| Professional | 0.45 (0.22 to 0.92) | 0.028 | ||||
| Restaurant /hotel | 1.00 (0.47 to 2.12) | 0.993 | ||||
| Other | 0.77 (0.48 to 1.25) | 0.294 |
*
Of 996 women with depression measures, n = 893 were eligible for this analysis. Reasons for exclusion included the following: n = 16 did not have a clinical stage outcome defined, and n = 87 only had depression measures taken on or later than the date of censorship.