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. 2018 Nov 18;2018:1024634. doi: 10.1155/2018/1024634

Figure 5.

Figure 5

CRT upregulates the expression of tight junction proteins Claudin-5 and ZO-1. Rat PMEC monolayers were divided into 6 groups: normal control, TNF-α, Dex, CRT high, CRT medium, and CRT low groups. After 48 h incubation, the expression of Claudin-5 and ZO-1 mRNA (a) and protein (b) was detected by qRT-PCR and Western blot, respectively. ∗, P<0.05, ∗∗, P<0.01, TNF-α group vs. normal control group; #, P<0.05, ##, P<0.01, treatment groups vs. TNF-a group; △, P<0.05, △△, P<0.01, CRT groups vs. Dex group.