Table 2.
Comparison between TBB and TBLC in 29 patients in whom both TBLC and TBB were obtained.
| TBB | TBLC | p value | |
|---|---|---|---|
| Sample size (mm) | 1.1 ± 0.6 | 5.3 ± 0.7 | <0.001 |
| Diagnostic yield ∗ | 38 % (11/29) | 69 % (20/29) | 0.017 |
| Sensitivity | 35% | 61% | 0.008 |
| Specificity | 100% | 100% | >0.999 |
| Positive PV | 100% | 100% | >0.999 |
| Negative PV | 29% | 40% | 0.277 |
| Bleeding | |||
| Grade 1 | 7% | 38% | 0.005 |
| Grade 2 | 0% | 14% | 0.043 |
| Grade 3 | 0% | 0% | >0.999 |
Note: abbreviations: TBB = transbronchial biopsy; TBLC = transbronchial lung cryobiopsy; PV = predictive value. ∗: diagnosis was obtained by TBLC alone in 9 patients and by both TBB and TBLC in 11 patients.