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. 2018 Nov 18;2018:1019034. doi: 10.1155/2018/1019034

Table 2.

Explanation of the hospital course management of lactic acidosis.

Date Management of lactic acidosis Lactate acid level MMOL/L CO2 level MEQ/L
1st day 0.9 % Normal saline 12.3 11

2nd day Normosol-R 11 11

1st week Dextrose 5% + sodium bicarbonate IV 17

2nd week 0.9 % Normal saline + Sodium Bicarbonate and 1st cycle of chemotherapy(Hyper-CVAD )∗∗, with Intrathecal Methotrexate 13

3rd week Few days after 1st cycle of Hyper CVAD with intrathecal Methotrexate 6.3 25

5th week 0.45 normal saline + Sodium bicarbonate+ 2nd cycle of Hyper CVAD -- 28

8th week 4th cycle of Hyper CVAD 24

Discharge -- -- 25

Each 100 mL of Normosol-R contains sodium chloride, 526 mg; sodium acetate, 222 mg; sodium gluconate, 502 mg; potassium chloride, 37 mg; and magnesium chloride hexahydrate, 30 mg. Hyper-CVAD: hyper-fractionated chemotherapy of cyclophosphamide, vincristine, doxorubicin, and dexamethasone.