Table 2.
Date | Management of lactic acidosis | Lactate acid level MMOL/L | CO2 level MEQ/L |
---|---|---|---|
1st day | 0.9 % Normal saline | 12.3 | 11 |
| |||
2nd day | Normosol-R ∗ | 11 | 11 |
| |||
1st week | Dextrose 5% + sodium bicarbonate IV | 17 | |
| |||
2nd week | 0.9 % Normal saline + Sodium Bicarbonate and 1st cycle of chemotherapy(Hyper-CVAD )∗∗, with Intrathecal Methotrexate | 13 | |
| |||
3rd week | Few days after 1st cycle of Hyper CVAD with intrathecal Methotrexate | 6.3 | 25 |
| |||
5th week | 0.45 normal saline + Sodium bicarbonate+ 2nd cycle of Hyper CVAD | - - | 28 |
| |||
8th week | 4th cycle of Hyper CVAD | 24 | |
| |||
Discharge | - - | - - | 25 |
∗Each 100 mL of Normosol-R contains sodium chloride, 526 mg; sodium acetate, 222 mg; sodium gluconate, 502 mg; potassium chloride, 37 mg; and magnesium chloride hexahydrate, 30 mg. ∗∗Hyper-CVAD: hyper-fractionated chemotherapy of cyclophosphamide, vincristine, doxorubicin, and dexamethasone.