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. 2018 Nov 18;2018:4528581. doi: 10.1155/2018/4528581

Figure 4.

Figure 4

Protective effects of aqueous FLJ extracts against HQ-induced DNA damage (a, b) L02 cells treated with 0 and 160 μM HQ and 0.25, 0.50, and 1.00 g/mL FLJ + HQ for 12 h. DNA damage was evaluated by alkaline single-cell gel electrophoresis (comet assay). (c) L02 cells treated with 0 and 160 μM HQ and 0.25, 0.50, and 1.00 g/mL FLJ + HQ for 12 h. 8-Hydroxy-2′-deoxyguanosine (8-OHdG) level as a specific marker of oxidative damage of DNA. 8-OHdG was evaluated using high-performance liquid chromatography with electrochemical detection (HPLC-ECD). All data were representative of at least three independent experiments. #P < 0.05 compared with the control. ∗P < 0.05 compared with 160 μM HQ treatment.