Table 1.
Selection |
(1) Representativeness of the exposed cohort |
(a) Truly representative of the average “GC patient” in the community (1 star) |
(b) Somewhat representative of the average “GC patient” in the community (1 star) |
(c) Selected group of users (e.g., nurses, volunteers) |
(d) No description of the derivation of the cohort |
(2) Selection of the nonexposed cohort |
(a) Drawn from the same community as the exposed cohort (1 star) |
(b) Drawn from a different source |
(c) No description of the derivation of the nonexposed cohort |
(3) Ascertainment of exposure (proof of GC and platinum-based chemotherapy) |
(a) Secure record (e.g., chemotherapy records) (1 star) |
(b) Structured interview |
(c) Written self-report |
(d) No description |
(4) Demonstration that outcome of interest was not present at start of study |
(a) Yes (1 star) |
(b) No |
Comparability |
(1) Comparability of cohorts on the basis of the design or analysis |
(a) Study controls for “chemotherapy regimens” (1 star) |
(b) Study controls for any additional factor (age, stage, etc.) (1 star) |
Outcome |
(1) Assessment of outcome (death or recurrence) |
(a) Independent blind assessment (1 star) |
(b) Record linkage (1 star) |
(c) Self-report |
(d) No description |
(2) Was follow-up long enough for outcomes to occur? (death or recurrence) |
(a) Yes (sufficient follow-up time was selected to observe the outcome) (1 star) |
(b) No |
(3) Adequacy of follow-up of cohorts |
(a) Complete follow-up all subjects accounted for (1 star) |
(b) Subjection lost to follow-up unlikely to introduce bias-small number lost “25%” or description provided of those lost (1 star) |
(c) Follow-up rate “75%” and no description of those lost |
(d) No statement |
GC: gastric cancer.