Table 1.
The effects of NaHS treatment on the development of neurobehavioral reflexes of pups with prenatal hHCY.
| Parameters | Control | Hcy | H2S | HcyH2S |
|---|---|---|---|---|
| Negative geotaxis (day of appearance) | 6 (5–7) n = 55 |
6 (6–8)∗ n = 65 |
6 (6–6)# n = 51 |
6 (5–7)# n = 47 |
| Head shake reflex (number of the head rotations per min at Р8) | 7 (5–11) n = 53 |
2 (1–4)∗ n = 60 |
9 (4–14)# n = 51 |
4 (2–6)∗,# n = 47 |
| Righting reflex (day of appearance) | 6 (4–7) n = 55 |
6 (6–8)∗ n = 65 |
6 (3–6)∗,# n = 51 |
4 (4–5)∗,# n = 49 |
| Righting reflex (time (s) at P6) | 1 (1–2) n = 55 |
2 (2–4)∗ n = 65 |
1 (1–0.75)# n = 51 |
1 (1–1.5)# n = 49 |
| Cliff avoidance test (day of appearance) | 6 (5–7) n = 55 |
7 (6–8)∗ n = 60 |
6 (5–6)# n = 51 |
4 (4–4)∗,# n = 49 |
| Acoustic startle reflex (day of appearance) | 10 (8–10) n = 53 |
10 (9–11)∗ n = 55 |
8 (6–10)∗,# n = 51 |
9 (8–12)# n = 47 |
| Cliff avoidance caused by visual stimulus (day of appearance) | 14 (12–15) n = 53 |
16 (16–17)∗ n = 53 |
14 (13–16)# n = 50 |
14 (14–15)# n = 46 |
| Free-fall righting (day of appearance) | 12 (12–16) n = 53 |
19 (16–19)∗ n = 53 |
14 (13–14)# n = 50 |
14 (13–14)# n = 46 |
| Test olfactory discrimination (day of appearance) | 14 (12–15) n = 53 |
16 (14–19)∗ n = 53 |
14 (14–16)# n = 50 |
14 (13–15)# n = 46 |
Data are expressed as median (Q1–Q3). Statistical significance between medians was calculated using the nonparametric ANOVA Kruskal-Wallis test, Kolmogorov-Smirnov normality test, and Mann-Whitney. ∗,#p < 0.05. ∗ compared to the control group, # compared to the Hcy group. n: number of animals.