Table 3.
Current status of clinical trials investigating EPCs and its relation to a single factor in disorders or diseases.
| Completed (90) | Recruiting (37) | Active, but not recruiting (13) | Not yet recruiting (8) | Terminated (14) | Withdrawn (10) | Unknown status (38) | NA (0) | Enrolled by invitation (1) | |
|---|---|---|---|---|---|---|---|---|---|
| Disorder of CVS | 47 | 15 | 7 | 1 | 8 | 5 | 15 | 0 | |
| e.g., MI, angina, hypertension, peripheral vascular disease (PVD), arteriosclerosis, coronary artery ischaemia | e.g., MI, cardiomyopathy, coronary artery disease (CAD), PVD, critical limb ischaemia (CLI), atherosclerosis | e.g., CAD, CLI, atherosclerosis | CLI | e.g., angina, CAD | e.g., ischaemic congestive heart failure (CHF), lower limb ischaemia | e.g., aortic aneurysm, CHF, CAD, PVD | |||
|
| |||||||||
| Renal disease | 2 | 1 | |||||||
| End-stage renal disease and chronic kidney disease | Acute kidney injury | ||||||||
|
| |||||||||
| GIT disorders | 3 | 2 | 1 | ||||||
| Liver cirrhosis, nonalcoholic fatty liver disease, and severe hepatic venoocclusive disease | End-stage liver disease and sinusoidal obstruction syndrome | Crohn's disease | |||||||
|
| |||||||||
| Endocrine disorders | 13 | 4 | 2 | 2 | 2 | 5 | |||
| e.g., type 1 and type II DM | e.g., type II DM | e.g., type II DM etc. | e.g., type II DM etc. | e.g., type II DM | e.g., type 1 and type II DM | ||||
|
| |||||||||
| Neoplastic disorders | 3 | 2 | 4 | 5 | |||||
| e.g., breast cancer, colorectal cancer, and nonsmall cell lung cancer | e.g., BRCA1, BRCA2 gene mutation, cervical cancer | e.g., renal cell carcinoma, multiple myeloma | e.g., breast cancer, lung cancer | ||||||
|
| |||||||||
| Healthy subjects | 7 | 1 | 1 | 1 | 1 | ||||
| e.g., healthy subjects | Obesity | Healthy | Quality of life | Morbid obesity | |||||
|
| |||||||||
| Respiratory disease | 2 | 1 | 1 | 3 | |||||
| Idiopathic pulmonary arterial hypertension | Pulmonary emphysema | Pulmonary hypertension | e.g., chronic obstructive pulmonary disease (COPD), idiopathic pulmonary arterial hypertension | ||||||
|
| |||||||||
| Reproductive disorders | 3 | 1 | |||||||
| e.g., polycystic ovary syndrome (PCOS) | e.g., PCOS | ||||||||
|
| |||||||||
| Musculoskeletal disorders | 1 | 1 | |||||||
| Ankylosing spondylitis | Bone defects | ||||||||
|
| |||||||||
| Neurologic diseases | 2 | 4 | 1 | 2 | 2 | 1 | |||
| Central nervous system and acute ischaemic stroke | Stroke, aneurysmal subarachnoid haemorrhage, and mild cognitive impairment | Brain and central nervous system tumours | Traumatic brain injury | Ischaemic stroke and migraine with aura | Diabetic foot ulcer | ||||
|
| |||||||||
| Hematological disorders | 4 | 5 | 2 | 1 | 1 | 4 | |||
| Endotoxemia, sickle cell anaemia, dyslipidemia, and hypoxia | Sickle cell disease without crisis, hypercholesterolemia, microgravity-exposed endothelial cells, hemolytic uremic syndrome, and soft-tissue sarcoma | Dystrophic epidermolysis bullosa and septic shock | Graft-versus-host disease | Sickle cell anaemia | Exercise anaphylaxis, recurrent adult Hodgkin lymphoma, acute myeloid leukemia, and brachial plexus (pressure) | ||||
|
| |||||||||
| Autoimmune disorders | 1 | 1 | |||||||
| Systemic scleroderma | Systemic lupus erythematosus | ||||||||
|
| |||||||||
| Dental disorders | 1 | ||||||||
| Tooth impacted | |||||||||
|
| |||||||||
| Miscellaneous | 3 | 1 | 1 | 1 | |||||
| Burn, bullous keratopathy, ischaemic ulcer | Sepsis | Delayed graft function | SDF-1 | ||||||