Table 5.
Transcript2 | Treatment | |||||
---|---|---|---|---|---|---|
Control | Pair-fed | Constant high temperature | Intermittent high temperature | SEM | P value | |
Day 1 | ||||||
NOX-1 | 1.15a | 0.92b | 0.83b | 0.80b | 0.08 | 0.02 |
NOX-4 | 1.01 | 0.90 | 1.02 | 1.00 | 0.06 | 0.40 |
COX-1 | 1.11 | 0.94 | 0.99 | 0.98 | 0.11 | 0.75 |
COX-2 | 1.01 | 0.88 | 0.94 | 0.81 | 0.08 | 0.32 |
5-LOX | 1.12 | 0.87 | 1.12 | 0.91 | 0.09 | 0.11 |
CYP7A1 | 1.05a | 0.74ab | 1.06a | 0.46b | 0.14 | 0.02 |
Complex Ι | 1.01ab | 1.16a | 0.77bc | 0.73c | 0.08 | <0.01 |
CoQ10 | 1.10 | 0.98 | 1.10 | 0.82 | 0.08 | 0.07 |
GR | 1.05a | 1.05a | 0.68b | 0.59b | 0.12 | 0.02 |
MnSOD | 1.02 | 1.15 | 1.03 | 0.97 | 0.09 | 0.84 |
CAT | 1.01a | 0.74b | 1.15a | 1.05a | 0.07 | <0.01 |
Day 21 | ||||||
NOX-1 | 1.06 | 1.21 | 1.04 | 0.97 | 0.12 | 0.56 |
NOX-4 | 1.01 | 1.19 | 1.30 | 1.29 | 0.10 | 0.14 |
COX-1 | 1.42b | 3.40a | 2.67a | 1.29c | 0.50 | <0.01 |
COX-2 | 1.03a | 0.96ab | 0.78b | 0.75b | 0.08 | 0.05 |
5-LOX | 1.27a | 0.47b | 0.57b | 0.43b | 0.21 | 0.02 |
CYP7A1 | 1.12b | 1.87a | 0.56c | 0.55c | 0.16 | <0.01 |
Complex Ι | 1.01 | 1.37 | 1.07 | 1.04 | 0.14 | 0.27 |
CoQ10 | 1.65 | 2.40 | 2.00 | 2.15 | 0.34 | 0.53 |
GR | 1.48 | 1.92 | 1.58 | 1.82 | 0.27 | 0.64 |
MnSOD | 1.01 | 1.25 | 1.27 | 1.32 | 0.10 | 0.13 |
CAT | 1.01 | 1.15 | 1.16 | 1.10 | 0.09 | 0.66 |
Day 55 | ||||||
NOX-1 | 0.89b | 0.86b | 1.12ab | 1.26a | 0.09 | 0.02 |
NOX-4 | 1.01 | 0.94 | 0.98 | 1.02 | 0.05 | 0.85 |
COX-1 | 1.06 | 0.84 | 1.25 | 1.22 | 0.12 | 0.09 |
COX-2 | 1.09 | 1.13 | 1.27 | 1.26 | 0.11 | 0.59 |
5-LOX | 1.01 | 1.14 | 0.90 | 1.19 | 0.21 | 0.08 |
CYP7A1 | 1.04 | 0.86 | 0.82 | 0.91 | 0.11 | 0.52 |
Complex Ι | 1.02 | 0.91 | 1.23 | 1.09 | 0.09 | 0.14 |
CoQ10 | 1.07 | 1.07 | 1.00 | 1.04 | 0.22 | 0.98 |
GR | 1.06 | 1.14 | 1.00 | 0.91 | 0.12 | 0.59 |
MnSOD | 1.01 | 1.13 | 1.21 | 1.13 | 0.21 | 0.36 |
CAT | 1.01 | 0.95 | 1.03 | 1.10 | 0.07 | 0.48 |
a, bValues within a row with different superscripts differ significantly at P < 0.05.
1 n = 6 for each treatment.
2 COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; NOX-1, NADPH oxidase-1; NOX-4, NADPH oxidase-4; 5-LOX, 5-lipoxygenase; CYP7A1, cytochrome P450 7A1; GR, glutathione reductase; Complex I, NADH dehydrogenase subunit Ι; CoQ10, Coenzyme Q10.