Table 1.
Clinical Characteristics of Study Participants
| Diagnosis |
ANOVA |
Tukey HSD (Adjusted
for Multiple Comparisons) |
|||||
|---|---|---|---|---|---|---|---|
| Control (n = 48) | PCOM Only (n = 42) | PCOS (n = 73) | P Value | Control vs PCOM | Control vs PCOS | PCOM vs PCOS | |
| Age, y | 29.4 ± 4.9 | 29.8 ± 5.3 | 27.4 ± 4.9 | 0.04 | 0.97 | 0.11 | 0.08 |
| BMI, kg/m2 | 23.7 ± 4.1 | 22.6 ± 4.2 | 25.6 ± 6.5 | 0.02 | 0.34 | 0.39 | 0.01 |
| Testosterone, ng/mL | 0.3 ± 0.1 | 0.3 ± 0.1 | 0.56 ± 0.2 | <0.0001 | 0.98 | <0.0001 | <0.0001 |
| Free testosterone, V | 0.35 ± 0.2 | 0.3 ± 0.2 | 0.9 ± 0.5 | <0.0001 | 0.85 | <0.0001 | <0.0001 |
| Hirsutism (Ferriman-Gallwey) | 2.9 ± 1.3 | 3.5 ± 1.8 | 8.1 ± 4.3 | <0.0001 | 0.31 | <0.0001 | <0.0001 |
| Menses per y | 12.1 ± 0.5 | 10.9 ± 1.8 | 8.1 ± 3.4 | <0.0001 | 0.07 | <0.0001 | <0.0001 |
| LH, IU/L | 7.7 ± 5.8 | 10.8 ± 14.3 | 11.9 ± 8.4 | <0.0001 | 0.13 | <0.0001 | 0.02 |
| FSH, IU/L | 5.7 ± 1.9 | 6.4 ± 2.9 | 5.5 ± 1.9 | 0.29 | 0.52 | 0.91 | 0.25 |
| LH/FSH ratio | 1.4 ± 0.6 | 1.5 ± 0.8 | 2.3 ± 1.4 | <0.0001 | 0.59 | <0.0001 | 0.0006 |
| Fasting glucose, mmol/L | 4.86 ± 0.34 | 4.85 ± 0.4 | 5.14 ± 1.87 | 0.37 | 1 | 0.47 | 0.47 |
| Fasting insulin, pmol/L | 48.5 ± 18.5 | 46.6 ± 21.9 | 61.4 ± 38.2 | 0.05 | 0.83 | 0.2 | 0.06 |
| HOMA-IR | 1.75 ± 0.7 | 1.69 ± 0.84 | 2.27 ± 1.54 | 0.01 | 0.97 | 0.05 | 0.03 |
| Hyperandrogenism | 0 | 0 | 62 | <0.0001 | 1 | <0.0001 | <0.0001 |
| Oligomenorrhea | 0 | 0 | 34 | <0.0001 | 1 | <0.0001 | <0.0001 |
| PCOM | 0 | 42 | 71 | <0.0001 | <0.0001 | <0.0001 | 0.39 |
Data are presented as mean ± standard deviation. Nonnormal data were ranked and analyzed by one-way analysis of variance followed by the Tukey HSD test.
Abbreviations: HSD, honest significant difference; V, Vermeulen equation.