Figure 1.

Fibroblast proliferation.

Notes: (A) Concentration-dependent increases in human lung fibroblast proliferation following treatment with FBS, PDGF or LPA for 24 hours, assayed using BrdU incorporation. (B) Concentration-dependent increases in proliferation following treatment with FBS for 24 or 48 hours, assayed using BrdU incorporation or nuclear count. Data were normalized to maximal proliferation observed with 10% serum, and expressed as mean ± SEM for >3 independent experiments.

Abbreviations: BrdU, bromodeoxyuridine; LPA, lysophosphatidic acid; PDGF, platelet-derived growth factor.