. 2018 May 18;103(8):3070–3077. doi: 10.1210/jc.2018-00579

Table 2.

Relations Between Sex Hormones, SHBG, and FMD

	FMD β(SE)
	Model 1	Model 2	Model 3
E1	0.60 (0.36)	0.69 (0.35)^a	0.77 (0.37)^a
E2	0.06 (0.15)	0.11 (0.15)	0.14 (0.16)
T	0.15 (0.69)	–0.08 (0.65)	–0.05 (0.67)
SHBG	1.27 (0.36)^b	1.12 (0.36)^c	1.31 (0.40)^c
FT^d	−1.41 (0.47)^c	−1.42 (0.47)^c	−1.58 (0.52)^c

Hormones log-transformed. Model 1: unadjusted. Model 2: baseline lumen diameter, age, race, BMI, leisure time physical activity, β-agonist meds, parity, and anxiety. Model 3: Model 2 plus education, SBP, HOMA, LDL-C, triglycerides, lipid-lowering medications, blood pressure-lowering medications, and diabetes medications.

Abbreviation: SBP, systolic blood pressure.

^{^a}

P < 0.05.

^{^b}

P < 0.001.

^{^c}

P < 0.01.

^{^d}

FT estimated using ensemble allostery models.