Table 2.
Hyperthyroidism | Hypothyroidism | Thyroiditis | Nontoxic Nodular Goiter | Simple Goiter | Other/Unspecified Goiter | Thyroid Adenoma | |
---|---|---|---|---|---|---|---|
Total no. of subjects | 85,169 | 63,143 | 12,532 | 65,782 | 11,582 | 21,953 | 6481 |
Sex | |||||||
Men | 17% | 15% | 16% | 16% | 15% | 14% | 25% |
Women | 83% | 85% | 84% | 84% | 85% | 86% | 75% |
Age at benign thyroid disease diagnosis | |||||||
Median, y (IQR) | 57.3 (42.7–70.9) | 58.9 (42.2–73.4) | 45.0 (33.8–56.2) | 49.1 (39.2–60.3) | 47.1 (35.9–60.0) | 48.4 (37.7–61.2) | 46.4 (36.0–56.9) |
Calendar year at benign thyroid disease diagnosis | |||||||
1978–1982 | 9% | 5% | 4% | 11% | 1% | 13% | 8% |
1983–1987 | 7% | 5% | 4% | 10% | 1% | 9% | 10% |
1988–1992 | 8% | 7% | 5% | 9% | 2% | 7% | 11% |
1993–1997 | 16% | 11% | 12% | 16% | 23% | 13% | 17% |
1998–2002 | 21% | 17% | 17% | 17% | 25% | 19% | 14% |
2003–2007 | 21% | 24% | 24% | 16% | 23% | 23% | 15% |
2008–2013 | 18% | 32% | 34% | 21% | 24% | 16% | 26% |
Follow-up | |||||||
Median, y (IQR) | 9.1 (4.7–14.7) | 6.3 (3.2–11.0) | 7.8 (4.0–13.9) | 11.6 (5.4–18.9) | 9.4 (4.8–14.9) | 10.6 (6.0–17.2) | 10.7 (4.6–18.5) |
Comorbid thyroid diseases | |||||||
Hyperthyroidism | — | 12% | 10% | 7% | 12% | 7% | 4% |
Hypothyroidism | 2% | — | 26% | 2% | 3% | 2% | 1% |
Thyroiditis | 1% | 6% | — | 1% | 1% | 1% | 1% |
Nontoxic nodular goiter | 5% | 8% | 6% | — | 23% | 16% | 24% |
Simple goiter | 1% | 2% | 1% | 3% | — | 3% | 2% |
Other/unspecified goiter | 3% | 3% | 2% | 8% | 10% | — | 5% |
Thyroid adenoma | 0.3% | 0.5% | 1% | 2% | 2% | 1% | — |
Abbreviation: IQR, interquartile range.