. 2018 Mar 23;103(6):2284–2290. doi: 10.1210/jc.2018-00071

Table 2.

Changes in Glycemic Traits Associated With Each Additional Copy of the MTNR1B rs10830963 G Allele by Gestational Weight Gain

	Inadequate		Adequate		Excessive		P Interaction
	β (SE)	P Value	β (SE)	P Value	β (SE)	P Value	P Interaction
Fasting glucose, mM
Age-adjusted	0.03 (0.16)	0.87	0.14 (0.08)	0.08	– 0.04 (0.06)	0.49	0.559
Multivariable adjusted^a	0.14 (0.17)	0.41	0.13 (0.06)	0.02	0.01 (0.05)	0.83	0.069
2-hour OGTT, mM
Age-adjusted	0.32 (0.34)	0.36	0.33 (0.20)	0.10	– 0.11 (0.13)	0.40	0.046
Multivariable adjusted^a	0.36 (0.33)	0.28	0.20 (0.17)	0.25	– 0.19 (0.11)	0.09	0.028
HbA1c, %
Age-adjusted	– 0.11 (0.12)	0.34	0.19 (0.07)	0.005	– 0.04 (0.05)	0.49	0.602
Multivariable adjusted^a	– 0.02 (0.12)	0.82	0.12 (0.05)	0.02	– 0.05 (0.04)	0.22	0.143

β represents the change in each glycemic trait per additional copy of the rs10830963 G allele.

Abbreviation: SE, standard error.

^{^a}

Adjustment for age, follow-up time, prepregnancy BMI, dietary fat (percent energy), sitting time, postpartum weight change, the level of corresponding glucose trait (continuous variable), family history of diabetes, current smoking, current alcohol drinking, leisure-time physical activity, and GDM therapy (categorical variables).