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. 2018 Sep 7;27(24):4323–4332. doi: 10.1093/hmg/ddy317

Table 1.

Genetic variants associated with menstrual cycle length

Region Nearest gene(s) SNP Alleles, other allele/effect allele (EAF) UKBB EGCUT Meta-analysis
Effect (SD of the binned menstrual cycle length) P-value Effect (SD of the binned menstrual cycle length) P P P heterogeneity
11:30226528 FSHB rs11031006 A/G (0.86) −0.16 (0.01) 1.1 × 10−38 −0.06 (0.02) 6.6 Inline graphic 10−4 3.6 Inline graphic 10−36 3.7 × 10−6
1:199891438 NR5A2 rs6670899 A/C (0.57) −0.05 (0.01) 1.1 × 10−10 −0.04 (0.01) 4.7 Inline graphic 10−4 6.6 Inline graphic 10−13 0.43
8:25248615 DOCK5/ GNRH1 rs13261573 A/G (0.75) −0.07 (0.01) 1.7 × 10−11 −0.02 (0.01) 7.0 Inline graphic 10−2 1.2 Inline graphic 10−10 0.02
11:101044203 PGR/PGR-AS1 rs471811 C/T (0.31) −0.03 (0.01) 4.8 × 10−5 −0.06 (0.01) 6.3 Inline graphic 10−5 3.0 Inline graphic 10−8 0.33
11:2118860 IGF2/INS-IGF2 rs11042596 G/T (0.34) 0.04 (0.01) 1.1 × 10−7 0.02 (0.01) 3.5 Inline graphic 10−2 4.5 Inline graphic 10−8 0.21

SD - standard deviation.