Independent association of the use of an ribavirin-free regimen (the reference
regimen: sofosbuvir + ribavirin) with the end-of-treatment patient-reported outcomes
(PROs) after adjustment for clinical and demographic PRO predictors. Multiple
regression beta values are shown with their 95% confidence intervals.
P < .05 for all PROs except for 6 PROs (SF-36: bodily pain,
general health, physical component summary; FACIT-F: emotional well-being, social
well-being; CLDQ-HCV: worry). Abbreviations: CLDQ-HCV, chronic liver disease
questionnaire-hepatitis C virus version; FACIT-F, functional assessment of chronic
illness therapy-fatigue; PRO, patient-reported outcome; SF-36, short-form-36;
WPAI:SHP, work productivity activity index:specific health problem.