Table 4.

Patient Characteristics Associated With Incident Hypertension

Characteristic	Bivariable		Multivariable
	IRR	95% CI	IRR	95% CI	P Value
Age, per 10 y increase	1.37	1.29–1.48	1.34	1.24–1.44	<.001
Female sex	1.11	.95–1.28	1.03	.84–1.26	.76
Race/ethnicity
Black	1.40	1.20–1.61	1.15	.97–1.37	.10
Hispanic	0.43	.29–0.65	0.54	.35–.84	.006
White	Ref		Ref
No insurance	0.90	.78–1.05	0.76	.62–.90	.003
BMI ≥ 30	1.92	1.63–2.26	1.70	1.43–2.02	<.001
Serum creatinine ≥ 1.4 (mg/dL)	1.23	1.06–1.43	1.36	1.16–1.61	<.001
Tobacco use	0.68	.58–0.78	0.73	.62–.86	<.001
Hyperlipidemia	0.97	.83–1.15	1.06	.89–1.27	.73
Diabetes	1.66	1.32–2.09	1.44	1.14–1.83	.002
HCV coinfection	0.98	.82–1.17	1.02	.81–1.30	.83
MSM	0.92	.81–1.07	1.18	.97–1.42	.10
IVDU	1.07	.87–1.32	1.20	.91–1.58	.20
Cocaine	1.12	.97–1.31	1.32	1.09–1.59	.004
Amphetamine	0.77	.49–1.20	1.01	.62–1.63	.97
CD4 nadir, cells/mm3
<200	0.90	.78–1.04	1.07	.92–1.27	.36
200–499	Ref		Ref
≥500	1.00	.76–1.29	0.73	.53–1.01	.06
VL most recent, <400 copies/mL	0.83	.71–0.96	0.87	.74–1.03	.11
Any ART exposure	0.61	.47–0.80	1.19	.84–1.70	.33
History of PI exposure	0.69	.54–0.90	1.28	.93–1.77	.12

Incidence rate ratios (and associated confidence intervals, P-values) were derived using multivariable Poisson regression.

Bold represents statistically significant P-value <.05.

Abbreviations: ART, antiretroviral therapy; BMI, body mass index; CI, confidence interval; HCV, hepatitis C virus; IRR, incident rate ratio; IVDU, intravenous drug use; MSM, men who have sex with men; PI, protease inhibitor; Ref, reference; VL, viral load.