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. 2018 Dec 3;13(12):e0207952. doi: 10.1371/journal.pone.0207952

Table 3. Validated gene targets of most abundant miRNA.

hsa-miR-378a-3p hsa-miR-340-5p hsa-miR-92b-3p hsa-miR-381-3p
CDK6 [95, 96] AKT1 [97, 98] CDKN1C [99101] ANO1
CYP19A1 [102] CCND1 DAB2IP [103, 104] CD1C [105]
GALNT7 CCND2y [96] DKK3 [106, 107] GJA1 [108, 109]
GLI3 [110] CCNG2 [111, 112] ITGA6 [113, 114] HDAC4
GOLT1A CDK6 [95] ITGAV [115] ID1
GRB2 [116, 117] HNRNPA2B1 [118] NLK NFKBIA
IGF1R [119] IL4 [120] PRMT5 [121] P2RX5
KSR1 KRAS [122] PTEN [123, 124] TBC1D9
MAPK1 [125, 126] MDM2 [127, 128] RAB23 [113, 129] TWIST1 [130, 131]
MSC MECP2 [132] RECK [133, 134] WEE1
MYC [135] MET SLC15A1
NPNT MITF [130] SMAD3 [136]
PGR [137] PTBP1 SMAD7 [88]
RUNX1 [138] PUM1 [139, 140]
SUFU PUM2
TGFB2 [141] RHOA [142, 143]
TOB2 [144] ROCK1 [115]
TUSC2 [145] SKP2 [146]
VEGFA [147] SOX2
VIM STAT3 [148150]
WNT10A
hsa-miR-421 hsa-miR-106b-3p hsa-miR-654-3p
ATM BMP2 [123] CDKN1A [151153]
CASP3 [154] PTEN [123, 124]
CBX7
CDH1 [155]
FOXO4 [156158]
RBMXL1
SIRT3 [159]
SMAD4 [160]

Table showing the 75 validated targets, found using miRTarBase [94], for the most abundant miRNA in our samples that were not found in adult plasma. Where available, the citation which supports a link between the gene and pregnancy is show.