Table 3.
Association Between the Genera Composing the Gut Microbiota and Plasma Concentrations of 9- and 13-Oxo-Octadecadienoic Acid
| 9-oxo-ODE | 13-oxo-ODE | |||||
|---|---|---|---|---|---|---|
| Genus (%) | r | r2 | p | r | r2 | p |
| Ruminococcus | −0.329 | 0.108 | 0.003 | −0.206 | 0.042 | 0.030 |
| Haemophilus | 0.081 | 0.006 | 0.013 | 0.139 | 0.019 | 0.011 |
| Varibaculum | −0.299 | 0.089 | 0.015 | −0.209 | 0.043 | 0.086 |
| Veillonella | 0.095 | 0.009 | 0.018 | 0.140 | 0.019 | 0.016 |
| Sarcina | −0.285 | 0.081 | 0.019 | −0.222 | 0.049 | 0.026 |
| Lactobacillus | −0.247 | 0.061 | 0.020 | −0.267 | 0.071 | 0.008 |
| Turicibacter | −0.292 | 0.085 | 0.023 | −0.235 | 0.055 | 0.038 |
| Actinomyces | −0.230 | 0.053 | 0.026 | −0.306 | 0.093 | 0.002 |
| Bifidobacterium | −0.310 | 0.096 | 0.031 | −0.226 | 0.051 | 0.053 |
| Lachnobacterium | 0.252 | 0.063 | 0.046 | 0.325 | 0.106 | 0.031 |
| Catenibacterium | 0.090 | 0.008 | 0.073 | 0.078 | 0.006 | 0.141 |
| Acidaminococcus | −0.043 | 0.001 | 0.133 | 0.026 | 0.001 | 0.085 |
| Perphyromonas | −0.178 | 0.031 | 0.135 | −0.061 | 0.004 | 0.666 |
| Dorea | −0.068 | 0.004 | 0.139 | −0.094 | 0.009 | 0.221 |
| Bacteroides | 0.081 | 0.006 | 0.169 | 0.188 | 0.035 | 0.060 |
| Clostridium | −0.190 | 0.036 | 0.182 | −0.157 | 0.024 | 0.142 |
| Parabacterioides | 0.100 | 0.010 | 0.234 | 0.188 | 0.035 | 0.132 |
| Odoribacter | 0.105 | 0.011 | 0.266 | 0.179 | 0.032 | 0.099 |
| Lactococcus | −0.174 | 0.030 | 0.280 | −0.143 | 0.020 | 0.309 |
| Peptoniphilus | −0.157 | 0.024 | 0.294 | −0.053 | 0.002 | 0.716 |
| Faecalibacterium | 0.040 | 0.001 | 0.301 | 0.051 | 0.002 | 0.322 |
| Butyricimonas | −0.129 | 0.016 | 0.356 | −0.112 | 0.012 | 0.511 |
| Coprococcus | −0.077 | 0.005 | 0.365 | −0.078 | 0.006 | 0.459 |
| Enterobacter | −0.189 | 0.035 | 0.381 | −0.102 | 0.010 | 0.411 |
| Sutterella | −0.044 | 0.020 | 0.385 | 0.199 | 0.039 | 0.100 |
| Holdemania | −0.205 | 0.042 | 0.425 | −0.090 | 0.008 | 0.707 |
| Coprobacillus | 0.087 | 0.007 | 0.448 | 0.069 | 0.004 | 0.958 |
| Roseburia | 0.188 | 0.035 | 0.465 | 0.218 | 0.047 | 0.278 |
| Streptococcus | −0.137 | 0.018 | 0.478 | −0.206 | 0.042 | 0.214 |
| Peptococcus | −0.048 | 0.002 | 0.493 | −0.011 | 0.0001 | 0.555 |
| Methanobrevibacter | −0.080 | 0.006 | 0.504 | −0.117 | 0.013 | 0.375 |
| Synergistes | 0.045 | 0.002 | 0.506 | 0.055 | 0.003 | 0.778 |
| Prevotella 2 | −0.074 | 0.005 | 0.517 | −0.012 | 0.0002 | 0.335 |
| Anaerostipes | 0.086 | 0.007 | 0.522 | 0.093 | 0.008 | 0.355 |
| Collinsella | −0.123 | 0.015 | 0.527 | −0.103 | 0.010 | 0.434 |
| Akkermansia | −0.126 | 0.015 | 0.561 | −0.042 | 0.001 | 0.405 |
| Phascolarctobacterium | −0.171 | 0.029 | 0.586 | −0.058 | 0.003 | 0.542 |
| Paraprevotella | −0.068 | 0.004 | 0.618 | −0.009 | 0.0001 | 0.804 |
| Eubacterium | −0.021 | 0.0004 | 0.621 | 0.053 | 0.002 | 0.711 |
| Megasphaera | −0.018 | 0.0003 | 0.625 | −0.066 | 0.004 | 0.580 |
| Eggerthella | 0.047 | 0.002 | 0.635 | 0.065 | 0.004 | 0.475 |
| Bilophila | 0.001 | <0.0001 | 0.646 | 0.021 | 0.0005 | 0.447 |
| Megamonas | 0.095 | 0.009 | 0.690 | 0.092 | 0.008 | 0.634 |
| Blautia | 0.082 | 0.006 | 0.789 | 0.026 | 0.006 | 0.982 |
| Oscillospira | −0.012 | 0.0001 | 0.891 | 0.043 | 0.001 | 0.896 |
| Prevotella | −0.010 | 0.0001 | 0.892 | 0.034 | 0.001 | 0.800 |
| Dialister | −0.108 | 0.011 | 0.931 | 0.033 | 0.001 | 0.418 |
| Lachnospira | −0.016 | 0.002 | 0.932 | 0.018 | 0.0003 | 0.942 |
| Escherichia | 0.016 | 0.0002 | 0.934 | −0.002 | <0.0001 | 0.869 |
| Desulfovibrio | −0.062 | 0.003 | 0.952 | −0.095 | 0.009 | 0.937 |
Correlations between variables were tested by using Spearman's rank correlations (n = 60). A Bonferroni-corrected p value of <9.8·10−4 was considered statistically significant and is indicated by bold italic.