. 2018 Dec 3;13(12):e0208420. doi: 10.1371/journal.pone.0208420

Table 1. Descriptive statistics for parameters of DED in the study groups CG, BAK, DM, GO, GVHD and SS.

Data expressed as mean ± SD (minimum–maximum).

Group	N	OSDI (0–100)	CFS (0–15)	TFBUT (sec)	ST (mm)
CG	24	12.8 ± 10.4 (0–45) ^b,d,e,f	0.1 ± 0.3 (0–1) ^e,f	10.5 ± 2.6 (5–15) ^b,c,d,e,f	24.4 ± 9.4 (12–40) ^b,e,f
BAK	17	34.6 ± 21.4 (2–87) ^a	0.4 ±0.8 (0–3) ^e,f	5.5 ± 3.4 (1–12) ^a	13.1 ± 12.5 (2–40) ^a
DM	11	30.0 ± 22.2 (10–73) ^a	0.7 ±1.3 (0–3) ^e	6.2 ± 4.4 (0–12) ^a	11.8 ± 9.5 (3–36)
GO	28	47.1 ± 18.8 (12–79) ^a	0.7 ±1.2 (0–4) ^e,f	5.4 ± 3.2 (2–12) ^a	15.7 ± 12.3 (2–40)
GVHD	28	48.2 ± 21.7 (7–85) ^a	4.4 ±3.8 (0–15) ^a,b,c,d	4.0 ± 2.8 (0–11) ^a	8.4 ± 8.7 (0–35) ^a
SS	98	48.8 ± 21.6 (0–91) ^a	2.1 ±2.0 (0–8) ^a,b,c,d	3.7 ± 2.4 (0–10) ^a	9.7 ± 10.2 (0–42) ^a

CG = Control Group; BAK = Glaucoma under Chronic Topical Treatment with Benzalkonium Chloride; DM = Diabetes Mellitus; GO = Graves’ Orbitopathy; GVHD = Graft versus Host Disease; SS = Sjögren’s syndrome; OSDI = Ocular Surface Disease Index; CFS = Corneal Fluorescein Staining; LGCS = Lissamine Green Conjunctival Staining; TFBUT = Tear Film Break-Up Time; ST = Schirmer Test; TFOsm = Tear film Osmolarity.

Kruskal–Wallis test with Dunn's multiple comparison post-hoc test.

Superscripted lowercase letters indicate statistical difference (p<0.05) vs CG^a, BAK^b, DM^c, GO^d, GVHD^e, SS^f.