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. 2018 Oct 12;59(12):2403–2412. doi: 10.1194/jlr.P085720

TABLE 4.

Differences in lipid levels from prepregnancy to after birth by birth order for parous HUNT2 and HUNT3 study participants with at least two birthsa

Women with 2+ Births (n = 18,956) Women with 3+ Births (n = 8,976)
Estimate 95% CI P Estimate 95% CI P
HDL-C (mg/dl)
 First birth −3.6 −4.8, −2.5 <0.001 −2.7 −4.8, −0.6 0.01
 Second birth −1.6 −2.4, −0.7 <0.001 −2.0 −3.4, −0.5 0.008
 Third birth −2.2 −3.2, −1.3 <0.001
Non-HDL-C (mg/dl)
 First birth 2.7 −0.6, 6.1 0.11 3.6 −2.4, 9.7 0.24
 Second birth −1.4 −3.9, 1.1 0.27 0.8 −3.6, 5.1 0.73
 Third birth 0.2 −2.6, 3.1 0.86
Triglycerides (mg/dl)
 First birth −0.3 −6.1, 5.5 0.92 5.9 −4.2, 16.0 0.25
 Second birth −2.2 −6.6, 2.3 0.34 0.1 −7.4, 7.6 0.98
 Third birth 0.1 −5.0, 5.2 0.98
TC/HDL-C ratio
 First birth 0.22 0.12, 0.31 <0.001 0.18 0.02, 0.34 0.03
 Second birth 0.03 −0.05, 0.10 0.49 0.09 −0.03, 0.21 0.12
 Third birth 0.08 −0.00, 0.16 0.05
a

Adjusted for participant’s age at measurement, HUNT survey, time since last meal, education, smoking initiation by the age of 20 years, and family history of CVD.