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. Author manuscript; available in PMC: 2018 Dec 3.
Published in final edited form as: Environ Res. 2018 Jul 27;167:248–254. doi: 10.1016/j.envres.2018.07.022

Table 4.

Diabetes odds ratios and Rothman synergy indices by categories of low and high BMI and arsenic

BMI* Arsenic* Diabetes
 Unadjusted
OR (95% CI)		 Adjusted#
OR (95% CI)
Yes No
Low Low 95 448 1.00 (Ref) 1.00 (Ref)
High Low 43 106 1.91 (1.26–2.91) 1.99 (1.30–3.05)
Low High 75 234 1.51 (1.07–2.13) 1.41 (0.99–2.00)
High High 18 20 4.24 (2.16–8.33) 4.48 (2.25–8.92)
Rothman synergy index 2.28 (0.82–6.36) 2.49 (0.87–7.09)

Abbreviations: BMI, body mass index; CI, confidence interval; OR, odds ratio; Ref, reference group

*

Low and high BMI defined as < and ≥30 kg/m2. Low and high arsenic defined as <5280 and ≥5280 cumulative arsenic water concentration lagged 40 years

#

Adjusted for age (<60, 60–70, >70 years old), sex, cancer status, smoking (never-smokers, >0 to <10, ≥10 cigarettes/day)