Fig. 2.

A classical case of multiple evanescent white dot syndrome (MEWDS) with absent signs on optical coherence tomography angiography (OCT-A). A 31-year-old woman presented with acute blurred vision in her right eye. Upon ocular examination, her best corrected visual acuity (BCVA) was 20/50 in the right eye and 20/20 in the left eye. Biomicroscopy of the anterior segment and intraocular pressure were normal in both eyes. (1a) Color fundus photography of the right eye revealed deep retinal white spots in the posterior pole and around the optic disc. (2) These lesions corresponded topographically to early hyperfluorescent lesions in fluorescein angiography (FA), (3) late hypofluorescent lesions on indocyanine green angiography (ICGA), and (4) hyperautofluorescent lesions on fundus autofluorescence (FAF). (5a and 5b) Cross-sectional optical coherence tomography (OCT) scans demonstrated disruption of the ellipsoid zone corresponding to the deep retinal white spots seen by color photography and FAF. These are all disease-defining characteristics of multiple evanescent white dot syndrome (MEWDS). (6a and 6b) When analyzing the optical coherence tomography angiography (OCT-A), we found no visible pathological alterations or differences between the two eyes. Recovery was complete after 10 weeks without any treatment.