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. 2018 Dec 3;8:17547. doi: 10.1038/s41598-018-35890-7

Figure 5.

Figure 5

Impairment of brain mitochondrial respiration by western diet feeding and Sirt3 deletion. Respiration rates are presented for the brain cortex samples from wild type (WT) and Sirt3−/− mice on standard (SD) and western diet (WD) at multiple states with the substrates, pyruvate (P) malate (M), glutamate (G) and succinate (S). #P < 0.05; *P < 0.01; **P < 0.001 vs wild type-SD.