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. 2018 Dec 3;8:17544. doi: 10.1038/s41598-018-35978-0

Figure 1.

Figure 1

Midostaurin reduces CD4 + CD25+ population in healthy PBMCs. (A) Representative contour plots of T cell populations from Healthy donors treated with inhibitors. (B) In vitro PBMCs were treated with 4 kinase inhibitors and normalized to IL-2/IL-7 control population percentages (N = 3, p < 0.05). (C) Combined quantification of multiple samples of PBMCs treated with 0.5, 1 and 2uM of midostaurin and normalized to IL-2/IL-7 control population percentages (N = 3, p < 0.001).