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. 2018 Dec 3;8:17537. doi: 10.1038/s41598-018-35557-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Specific features of various types of base pairs captured by genus plots for structure of large ribosomal subunit of the Haloarcula marismortui (PDB ID 1s72). Each new plot (from the bottom to the top) is obtained upon adding an additional type of base pairs to the analysis, according to the ordering in (2). Flat regions which are formed detect a domain structure of this ribosome; various colors on the horizontal axis correspond to domains, which are shown in the same color in the cartoon representation of the ribosome. The largest spaces between plots arise after including tSS and cSS detect helix packing and A-minor interactions, which indeed contribute most to the complexity of bonds. The most narrow spaces between plots correspond to rare cHH and tHH interactions.