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. 2018 Nov 27;10:394. doi: 10.3389/fnagi.2018.00394

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Copyright © 2018 Zhu and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Stack plots of rat brain tissue H₂¹⁷O spectra obtained from a single voxel selected from the 3D ¹⁷O MRSI datasets with two consecutive ¹⁷O₂ inhalations (~2 min each) for repeated CMRO₂ and cerebral blood flow (CBF) imaging measurements. ¹⁷O₂ in either blood or brain tissue is NMR invisible. Figure adapted from Zhu et al. (2007).